Code 43 is not the DIS, it’s the knock sensing system, knock sensor, knock control module or related wiring. Likely not related to the current issue.
The secondary fuel pump shuts down at 176F coolant temp leaving only the primary pump running. The primary pump would still be my first look. A pump amp draw test should tell you what’s going on.
Here’s the test write up.
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http://www.zr1.net/forum/showthread.php?p=136108